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保安队长曹晓东在大巴上见义勇为的过程中精神受到极大的刺激后导致失忆，醒来后的自己却变成了公安局通缉杀人犯。所有的证据都指向曹晓东是杀人凶手，失去记忆的曹晓东无法为自己做出任何辩解，于是选择逃离医院，寻找在大巴上目睹整件事情发生的乘客来证明自己的清白。然而，在每次案件即将有重大突破的时候，曹晓东所找到的证人，不是一个接一个的失踪，就是相继发生意外，在侦查陷入停滞状态时，新的发现让案情打破僵局……我就是其中之一，只怕也是唯一肯出手救你的那一个。　　 病愈后的白求恩怀着His eyes were red, his tears rolled down, his whole body trembled, and even his handcuffs and shackles were shaking. At this moment, he was like a child who had done something wrong, as if praying for the forgiveness of adults, but the law would give him the fairest judgment.Weng Siliang informed the buyer that he had called in more than a dozen Indonesian sailors to take over the "Changsheng Wheel", while the 18 gangsters returned to the mainland of China on the receiving ship.民国初年，内忧外患，天下大乱。乱世中，一支行骗江湖的杂技团偶然“捡”到了一位“大侠”。此人身负重伤，但在危机关头却以一手惊人赌技，使杂技团从生死豪赌中侥幸脱身。魔术女郎赵小灵(霍思燕饰演)情窦初开，不禁对他暗生爱慕…谁知这位“大侠”从昏迷中醒来，却变成了“大傻”，他懵懵懂懂，智力只相当于几岁顽童，惹出连篇笑话。而这时杀机涌现，数派神秘势力竟同时痛下杀手！杂技团死伤殆尽，“大侠”被血腥刺激，激发出绝顶武功，带着赵小灵和壮汉大牛(梁子饰演)杀出一条血路。不料刚刚死里逃生，恢复理智的“大侠”却痛苦地意识到自己丧失了全部记忆！脑海中只能回想起一双美丽的蓝眼睛……他一遍遍自问：“我是谁？我从哪里来？我往哪里去？”于是悬疑重重、步步惊魂的历险由此展开……今日他们为义，同赴生死。